Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473402 | 0.92 | NPC1 (0.41) | CHKAMAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL12473319 | 0.89 | PRMT7 (0.35) | MAPTHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL12473398 | 0.89 | PDE10A (0.37) | MAPTHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL12473407 | 0.88 | CNR2 (0.37) | MAPTHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL12473317 | 0.87 | KDM4E (0.42) | ACHEMAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL12473352 | 0.86 | F7 (0.33) | MAPTHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12473400 | 0.84 | RAB9A (0.36) | MAPTALDH1A1MEN1PSMD14KMT2A | |
| SCHEMBL12473348 | 0.83 | PDE4D (0.33) | MAPTHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL12473410 | 0.83 | PRMT7 (0.35) | MAPTHPGDKDM4EALDH1A1MEN1 | |
| SCHEMBL12473442 | 0.82 | ALDH1A1 (0.36) | MAPTHPGDKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |