Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.36 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473199 | 0.92 | CNR2 (0.37) | CNR2CTNNB1TCF7L2PRMT7MAPT | |
| SCHEMBL12473319 | 0.89 | PRMT7 (0.35) | CNR2CTNNB1TCF7L2PRMT7MAPT | |
| SCHEMBL12473398 | 0.89 | PDE10A (0.37) | PRMT7MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12473403 | 0.88 | BCHE (0.34) | PRMT7MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12473352 | 0.88 | F7 (0.33) | CNR2CTNNB1TCF7L2PRMT7MAPT | |
| SCHEMBL12473317 | 0.87 | KDM4E (0.42) | CNR2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12473400 | 0.84 | RAB9A (0.36) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12473410 | 0.83 | PRMT7 (0.35) | PRMT7MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12473412 | 0.82 | MAOB (0.38) | PRMT7MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL12473402 | 0.82 | NPC1 (0.41) | PRMT7MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |