Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473398 | 0.89 | PDE10A (0.37) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12473412 | 0.88 | MAOB (0.38) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL12473350 | 0.80 | PDE10A (0.39) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12473319 | 0.79 | PRMT7 (0.35) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL12473410 | 0.79 | PRMT7 (0.35) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12473432 | 0.79 | PDE10A (0.36) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12473199 | 0.78 | CNR2 (0.37) | MAPTMEN1KMT2ATSHRLMNA | |
| SCHEMBL12473402 | 0.78 | NPC1 (0.41) | MAPTKMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL12473407 | 0.78 | CNR2 (0.37) | MAPTMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL12473403 | 0.78 | BCHE (0.34) | MAPTMEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |