Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.35 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170041 | 0.86 | KMT2A (0.40) | KMT2AHCRTR1HCRTR2CCR5CBX7 | |
| SCHEMBL13368960 | 0.82 | RAB9A (0.40) | KMT2AKDM4ECBX7CDY1; CDY1BLMNA | |
| SCHEMBL13368858 | 0.81 | MT-CO2 (0.33) | HCRTR1HCRTR2GAA | |
| SCHEMBL13368845 | 0.78 | ELANE (0.38) | KMT2AKDM4ECBX7CDY1; CDY1BALDH1A1 | |
| SCHEMBL2169721 | 0.77 | CNR2 (0.45) | KMT2ACCR5KDM4ECBX7CDY1; CDY1B | |
| SCHEMBL12473228 | 0.72 | HPGD (0.42) | KMT2AALDH1A1GAAPOLBMEN1 | |
| SCHEMBL2169693 | 0.71 | ITGB1 (0.42) | KMT2ACCR5ALDH1A1POLBHTT | |
| SCHEMBL2172271 | 0.71 | KDM4E (0.39) | KMT2AKDM4EALDH1A1GAALMNA | |
| SCHEMBL2170594 | 0.70 | USP2 (0.36) | KDM4EALDH1A1GAAPOLB | |
| SCHEMBL2170645 | 0.70 | GAA (0.45) | HCRTR1HCRTR2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348019-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010050191-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | 興和株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |