Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036620 | 0.86 | PPARA (0.52) | KAT8CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL8470670 | 0.83 | KAT8 (0.58) | KAT8CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL28337001 | 0.82 | KAT8 (0.56) | KAT8CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL9008218 | 0.78 | KAT8 (0.58) | KAT8CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL3030328 | 0.78 | CNR2 (0.55) | CYP3A4 | |
| SCHEMBL5676633 | 0.77 | KAT8 (0.54) | KAT8CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL6923070 | 0.77 | HTR1A (0.72) | CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL7246840 | 0.77 | HTR1A (0.72) | CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL16609989 | 0.77 | HTR1A (0.72) | CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL9485313 | 0.77 | HTR1A (0.72) | CYP3A4CYP2C8CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621702-A2 | CONTAINER MODIFICATIONS TO MINIMIZE DEFECTS DURING REACTIVE POLYURETHANE FLOW | Dow Global Technologies LLC (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012044878-A2 | CONTAINER MODIFICATIONS TO MINIMIZE DEFECTS DURING REACTIVE POLYURETHANE FLOW | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-04-05 | — | — | WO | disclosed |