Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337001 | 0.98 | KAT8 (0.56) | KAT8CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL12474283 | 0.83 | KAT8 (0.53) | KAT8CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL29127649 | 0.83 | PPARA (0.75) | KAT8CYP2C19TRPV1PPARAPPARG | |
| SCHEMBL9008218 | 0.83 | KAT8 (0.58) | KAT8CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL7252668 | 0.82 | TRPV1 (0.56) | KAT8TRPV1PPARAPPARGLTA4H | |
| SCHEMBL7246712 | 0.82 | TRPV1 (0.56) | KAT8TRPV1PPARAPPARGLTA4H | |
| SCHEMBL5676633 | 0.82 | KAT8 (0.54) | KAT8CYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9485313 | 0.81 | HTR1A (0.72) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL16609989 | 0.81 | HTR1A (0.72) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL17253824 | 0.81 | ALOX5 (0.52) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999010305-A1 | METHOD FOR PRODUCING O-HYDROXYACETOPHENONE DERIVATIVES | COGNIS DEUTSCHLAND GMBH (DE) | 1999-03-04 | — | — | WO | disclosed |