Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037168 | 0.77 | CYP2D6 (0.57) | L3MBTL1CYP2D6ALDH1A1LMNACYP2C19 | |
| SCHEMBL3179387 | 0.73 | CYP2A13 (0.43) | ALDH1A1CYP2A13KDM4E | |
| SCHEMBL12475149 | 0.73 | CYP2A13 (0.35) | LMNACYP2A13KMT2AMEN1 | |
| SCHEMBL1478587 | 0.72 | MPO (0.35) | CYP2D6CYP2C19CYP3A4KMT2AMEN1 | |
| SCHEMBL3166127 | 0.72 | CYP2D6 (0.65) | L3MBTL1CYP2D6ALDH1A1LMNACYP2C19 | |
| SCHEMBL2184152 | 0.71 | KMT2A (0.50) | L3MBTL1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16462153 | 0.70 | CYP2A13 (0.61) | CYP2D6ALDH1A1LMNACYP2A13CYP2C19 | |
| SCHEMBL1419239 | 0.70 | KMT2A (0.52) | L3MBTL1LMNACYP2C19KMT2AMEN1 | |
| SCHEMBL5213420 | 0.70 | MEN1 (0.74) | L3MBTL1CYP2D6ALDH1A1KMT2AMEN1 | |
| SCHEMBL3831752 | 0.69 | MCL1 (0.41) | ALDH1A1CYP3A4KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | Vifor (International) AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110603-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | WO | disclosed |