Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477536 | 0.76 | PARP1 (0.34) | — | |
| SCHEMBL12475151 | 0.73 | L3MBTL1 (0.51) | CYP2A13MEN1KMT2ALMNA | |
| SCHEMBL3831752 | 0.72 | MCL1 (0.41) | SLC6A2MEN1KMT2A | |
| SCHEMBL11973123 | 0.72 | — | — | |
| SCHEMBL12475150 | 0.69 | CYP2A13 (0.37) | CYP2A13MEN1KMT2A | |
| SCHEMBL1476589 | 0.67 | CA2 (0.32) | — | |
| SCHEMBL1570242 | 0.67 | KDM4E (0.50) | KMT2A | |
| SCHEMBL1477884 | 0.65 | MPO (0.33) | — | |
| SCHEMBL1479870 | 0.64 | LMNA (0.42) | MEN1KMT2ALMNA | |
| SCHEMBL27627536 | 0.64 | ALDH1A1 (0.33) | CYP2A13SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | Vifor (International) AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110603-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | WO | disclosed |