Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 16/20 | 0.76 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475157 | 1.00 | CTSD (0.76) | CTSDCASP1SMN1; SMN2 | |
| SCHEMBL17770727 | 0.86 | CTSD (1.00) | CTSD | |
| SCHEMBL19281154 | 0.86 | CTSD (1.00) | CTSD | |
| SCHEMBL17758210 | 0.79 | CTSD (0.77) | CTSD | |
| SCHEMBL17758206 | 0.79 | CTSD (0.77) | CTSD | |
| SCHEMBL17758209 | 0.79 | CTSD (0.77) | CTSD | |
| SCHEMBL12475257 | 0.78 | CTSD (0.80) | CTSD | |
| SCHEMBL12475255 | 0.78 | CTSD (0.80) | CTSD | |
| SCHEMBL16296098 | 0.78 | CTSD (0.78) | CTSD | |
| SCHEMBL20725223 | 0.78 | CTSD (0.78) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673287-B1 | AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2017-08-30 | — | — | EP | claimed |
| EP-2673287-A1 | AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | Merck Patent GmbH (DE) | 2013-12-18 | — | — | EP | claimed |
| WO-2012107153-A1 | AMINO STATIN DERIVATIVESFOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | claimed |
| EP-2673287-B1 | AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |
| EP-2673287-A1 | AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | Merck Patent GmbH (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107153-A1 | AMINO STATIN DERIVATIVESFOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |