Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269194 | 0.89 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL25263228 | 0.86 | ALDH1A1 (0.47) | ALDH1A1EPHX1 | |
| SCHEMBL1155466 | 0.83 | CYP2C9 (0.40) | ALDH1A1EPHX1NPC1KMT2ALMNA | |
| SCHEMBL3227368 | 0.83 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21945463 | 0.81 | EPHX1 (0.31) | ALDH1A1EPHX1 | |
| SCHEMBL18239998 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL311112 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6263692 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL22129579 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL22129606 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273342-B2 | Methods and systems for evaluating and predicting the reactivity of monooxygenase enzymes | UNIVERSITY OF ROCHESTER (US) | 2016-03-01 | — | — | US | claimed |
| US-20140038850-A1 | METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES | UNIVERSITY OF ROCHESTER (US) | 2014-02-06 | — | — | US | claimed |
| WO-2012109586-A2 | METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES | UNIVERSITY OF ROCHESTER (US) | 2012-08-16 | — | — | WO | claimed |
| EP-4694886-A1 | MICROTUBULE TARGETING AGENTS | BPGbio, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20240342138-A1 | MICROTUBULE TARGETING AGENTS | THLIVERIS, ANDREW T. | 2024-10-17 | — | — | US | disclosed |
| WO-2024216283-A1 | MICROTUBULE TARGETING AGENTS | BPGBIO, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| US-9273342-B2 | Methods and systems for evaluating and predicting the reactivity of monooxygenase enzymes | UNIVERSITY OF ROCHESTER (US) | 2016-03-01 | — | — | US | disclosed |
| US-20140038850-A1 | METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES | UNIVERSITY OF ROCHESTER (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2012109586-A2 | METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES | UNIVERSITY OF ROCHESTER (US) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240342138-A1 | MICROTUBULE TARGETING AGENTS | MAP2, TUBB3, TUBB1 | ALDH1A1 3381/4885EPHX1 4565/4885MEN1 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.