SCHEMBL12475416

SCHEMBL12475416

CCCCCCC(C)OC(=O)c1ccc(OC(=O)c2ccc(OC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
PNLIP P16233 1/20 0.51
TSHR P16473 1/20 0.49
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 2/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
MGLL Q99685 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 3/20 0.45
KMT2A Q03164 2/20 0.45
PRSS1 P07477 2/20 0.45
ACR P10323 2/20 0.45
GFER P55789 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20354073 1.00 ALDH1A1 (0.51) ALDH1A1PNLIPTSHRLMNASMN1; SMN2
SCHEMBL6872017 0.91 ALDH1A1 (0.52) ALDH1A1TSHRLMNASMN1; SMN2NPC1
SCHEMBL6872611 0.91 ALDH1A1 (0.52) ALDH1A1TSHRLMNASMN1; SMN2NPC1
SCHEMBL13991163 0.90 ALDH1A1 (0.61) ALDH1A1TSHRLMNASMN1; SMN2NPC1
SCHEMBL26186216 0.90 ALDH1A1 (0.51) ALDH1A1TSHRLMNASMN1; SMN2NPC1
SCHEMBL12408695 0.90 ALDH1A1 (0.51) ALDH1A1PNLIPTSHRLMNASMN1; SMN2
SCHEMBL803468 0.90 ALDH1A1 (0.51) ALDH1A1TSHRLMNASMN1; SMN2NPC1
SCHEMBL6936577 0.90 ALDH1A1 (0.51) ALDH1A1PNLIPTSHRLMNASMN1; SMN2
SCHEMBL6872703 0.90 TSHR (0.51) ALDH1A1TSHRLMNASMN1; SMN2NPC1
SCHEMBL25612616 0.89 TSHR (0.56) ALDH1A1PNLIPTSHRNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3163368-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-06-26 EP disclosed
EP-2792727-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2017-10-18 EP disclosed
EP-3163368-A1 LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-05-03 EP disclosed
US-8961824-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-24 US disclosed
US-20140027672-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2014-01-30 US disclosed
EP-2348090-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2011-07-27 EP disclosed
US-7709064-B2 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2010-05-04 US disclosed
US-20070290169-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-12-20 US disclosed
US-20070012898-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-01-18 US disclosed