SCHEMBL803468

SCHEMBL803468

CCCCCCC(C)OC(=O)c1ccc(OC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
TSHR P16473 1/20 0.49
NPC1 O15118 3/20 0.48
LMNA P02545 3/20 0.48
NFKB1 P19838 3/20 0.48
NFKB2 Q00653 3/20 0.48
RELA Q04206 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPT P10636 6/20 0.45
KMT2A Q03164 2/20 0.45
MGLL Q99685 1/20 0.45
PRSS1 P07477 2/20 0.45
ACR P10323 2/20 0.45
MEN1 O00255 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26186216 1.00 ALDH1A1 (0.51) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL6872017 0.91 ALDH1A1 (0.52) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL6872611 0.91 ALDH1A1 (0.52) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL12475416 0.90 ALDH1A1 (0.51) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL12408695 0.90 ALDH1A1 (0.51) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL13991163 0.90 ALDH1A1 (0.61) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL20354073 0.90 ALDH1A1 (0.51) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL20434807 0.90 NPC1 (0.48) ALDH1A1NPC1LMNANFKB1NFKB2
SCHEMBL6936577 0.90 ALDH1A1 (0.51) ALDH1A1TSHRNPC1LMNANFKB1
SCHEMBL25565413 0.90 NPC1 (0.48) ALDH1A1NPC1LMNANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-20240026223-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-01-25 US disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11829021-B2 Polymer dispersed liquid crystal display device comprising a polymer network having a helical structure and method for manufacturing the same Sharp Display Technology Corporation (JP) 2023-11-28 US disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-11796856-B1 Organic solid crystals having helical structures formed using cholesteric liquid crystals META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-24 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11788009-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-10-17 US disclosed
US-20100301270-A1 LIQUID-CRYSTALLINE MEDUIM MERCK PATENT GMBH (DE) 2010-12-02 US disclosed
US-20100258763-A1 LIQUID CRYSTAL SYSTEM AND LIQUID CRYSTAL DISPLAY SCHOTT CECILE 2010-10-14 US disclosed
US-7794802-B2 Polymerizable liquid crystal compound, composition and polymer CHISSO CORPORATION (JP) 2010-09-14 US disclosed
US-20100096591-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND POLYMER CHISSO CORPORATION 2010-04-22 US disclosed
US-20100085529-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING 1,2-DIFLUOROETHENE COMPOUNDS WITTEK MICHAEL 2010-04-08 US disclosed
US-20100076171-A1 Polymerizable liquid crystal compound, composition and polymer CHISSO CORPORATION 2010-03-25 US disclosed
US-20100026953-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT (DE) 2010-02-04 US disclosed
US-7541071-B2 Liquid-crystalline (METH) acrylate derivatives and composition containing them CHISSO CORPORATION (JP) 2009-06-02 US disclosed
US-7413782-B2 Polymerizing binaphthalene derivatives CHISSO CORPORATION (JP) 2008-08-19 US disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096591-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND POLYMER PKN1, ZYX, OXER1 ALDH1A1 839/4885TSHR 4531/4885NPC1 2465/4885
US-20100076171-A1 Polymerizable liquid crystal compound, composition and polymer LSS, SFXN1, FRG1 ALDH1A1 4624/4885TSHR 4340/4885NPC1 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.