Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621456 | 0.83 | GABRA1 (0.55) | CYP1A2CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20621455 | 0.83 | GABRA1 (0.55) | CYP1A2CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL989479 | 0.79 | CYP1A2 (0.43) | TYRGAANQO1CYP1A2CYP3A4 | |
| SCHEMBL20681680 | 0.77 | NQO1 (0.40) | TYRNQO1CYP1A2CYP3A4AHR | |
| SCHEMBL8018546 | 0.77 | TYR (0.43) | TYRGAANQO1SLC6A2SLC6A4 | |
| SCHEMBL51618 | 0.76 | TYR (0.70) | TYRSLC6A2 | |
| SCHEMBL1772723 | 0.76 | ESR1 (0.54) | TYRCYP1A2CYP3A4AHRSLC6A2 | |
| SCHEMBL13532442 | 0.75 | TYR (0.70) | TYRMGAMGAASIMGAM2 | |
| SCHEMBL725091 | 0.74 | SLC6A2 (0.54) | CYP1A2CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18815425 | 0.74 | TYR (1.00) | TYRMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | claimed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | claimed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | claimed |
| EP-2673261-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | Pierre Fabre Dermo-Cosmétique (FR) | 2013-12-18 | — | — | EP | claimed |
| WO-2012107421-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-08-16 | — | — | WO | claimed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | disclosed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| EP-2673261-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | Pierre Fabre Dermo-Cosmétique (FR) | 2013-12-18 | — | — | EP | disclosed |
| CN-103380114-A | Resorcinol heterocyclic derivatives, their preparation and their cosmetic use | FABRE PIERRE DERMO COSMETIQUE | 2013-10-30 | — | — | CN | disclosed |
| WO-2012107421-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | NQO1, SQOR, CBR1 | TYR 38/4885MGAM 3759/4885GAA 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.