Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17340388 | 0.80 | ALOX5 (0.37) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL12475656 | 0.80 | POLB (0.42) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL12475318 | 0.79 | USP2 (0.42) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| Fenocinol SCHEMBL2110781 | 0.76 | CA12 (0.44) | KMT2AMEN1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL12475392 | 0.75 | CASR (0.40) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL9115762 | 0.74 | CA12 (0.54) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL12475680 | 0.74 | CA12 (0.40) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL29539579 | 0.72 | CA12 (0.56) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL35743 | 0.72 | CA12 (0.56) | KMT2AMEN1MAPTKDM4ECYP3A4 | |
| SCHEMBL29280648 | 0.72 | SMN1; SMN2 (0.47) | KMT2AMEN1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| US-9422261-B2 | Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2016-08-23 | — | — | US | disclosed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | disclosed |
| EP-2673261-B1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-12-16 | — | — | EP | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2014-02-20 | — | — | US | disclosed |
| EP-2673261-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | Pierre Fabre Dermo-Cosmétique (FR) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107421-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140050683-A1 | HETEROCYCLIC RESORCINOL DERIVATIVES, PREPARATION OF SAME AND COSMETIC USES THEREOF | NQO1, SQOR, CBR1 | KMT2A 1968/4885MEN1 531/4885MAPT 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.