Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CDC7 | O00311 | 10/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 10/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885708 | 0.79 | TRPM8 (0.78) | TRPM8MAPTCDC7DBF4PTPN11 | |
| Bromide SCHEMBL1257330 | 0.78 | ALDH1A1 (0.64) | MAPTCDC7DBF4KDM4EMEN1 | |
| SCHEMBL15048955 | 0.78 | TRPM8 (1.00) | TRPM8MAPTCDC7DBF4PTPN11 | |
| SCHEMBL15049091 | 0.77 | MAPT (0.53) | TRPM8MAPTCDC7DBF4PTPN11 | |
| SCHEMBL10878746 | 0.77 | KDM4E (0.48) | TRPM8MAPTPTPN11PTGDR2KDM4E | |
| SCHEMBL299752 | 0.77 | ALDH1A1 (0.60) | TRPM8MAPTCDC7DBF4KDM4E | |
| SCHEMBL11159408 | 0.76 | MAPT (0.62) | TRPM8MAPTCDC7DBF4PTPN11 | |
| SCHEMBL12475713 | 0.76 | TRPM8 (0.70) | TRPM8MAPTCDC7DBF4PTPN11 | |
| SCHEMBL4503056 | 0.75 | CDC7 (0.88) | TRPM8CDC7DBF4DHODHKDM4E | |
| SCHEMBL2886595 | 0.75 | TRPM8 (0.71) | TRPM8MAPTCDC7DBF4PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012109573-A1 | SUBSTITUTED THIAZOLES FOR USE AS ANTIVIRAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2012-08-16 | — | — | WO | disclosed |