Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040604 | 0.85 | ACHE (0.54) | ACHEALDH1A1CYP3A4NR3C1KMT2A | |
| SCHEMBL1038127 | 0.80 | ACHE (0.58) | ACHEALDH1A1CYP3A4KMT2AGAA | |
| SCHEMBL17286695 | 0.76 | SMN1; SMN2 (0.59) | ACHEALDH1A1CYP3A4NR3C1NR3C2 | |
| SCHEMBL22909945 | 0.76 | NR3C2 (0.45) | ACHEALDH1A1CYP3A4NR3C1KMT2A | |
| SCHEMBL5242186 | 0.76 | ALDH1A1 (0.36) | ACHEALDH1A1CYP3A4NR3C1KMT2A | |
| SCHEMBL24766024 | 0.75 | ACHE (0.47) | ACHEALDH1A1CYP3A4KMT2AGAA | |
| SCHEMBL25839791 | 0.75 | ACHE (0.56) | ACHEALDH1A1CYP3A4KMT2AGAA | |
| SCHEMBL764998 | 0.75 | ACHE (0.56) | ACHEALDH1A1CYP3A4NR3C1KMT2A | |
| SCHEMBL10363878 | 0.74 | ALDH1A1 (0.46) | ACHEALDH1A1CYP3A4NR3C1KMT2A | |
| SCHEMBL3534896 | 0.73 | ACHE (0.54) | ACHEALDH1A1CYP3A4NR3C1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |