Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348453 | 0.82 | LTB4R2 (0.58) | LTB4R2AGTR1SLC33A1 | |
| SCHEMBL7435938 | 0.82 | LTB4R2 (0.53) | LTB4R2AGTR1SLC33A1 | |
| SCHEMBL21034046 | 0.80 | LTB4R2 (0.51) | LTB4R2 | |
| SCHEMBL2773609 | 0.77 | LTB4R2 (0.50) | LTB4R2AGTR1 | |
| SCHEMBL13278407 | 0.72 | LTB4R2 (0.52) | LTB4R2SLC33A1PPARG | |
| SCHEMBL4316055 | 0.72 | LTB4R2 (0.49) | LTB4R2AGTR1PPARG | |
| SCHEMBL12994003 | 0.72 | AGTR1 (0.47) | LTB4R2AGTR1 | |
| SCHEMBL12348839 | 0.71 | SLC33A1 (0.55) | AGTR1SLC33A1PPARG | |
| SCHEMBL4447972 | 0.71 | SLC33A1 (0.51) | LTB4R2AGTR1SLC33A1PPARG | |
| SCHEMBL1891417 | 0.71 | AGTR1 (0.66) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673274-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL | Jubilant Life Sciences Limited (IN) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107814-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL | JUBILANT LIFE SCIENCES LIMITED (IN) | 2012-08-16 | — | — | WO | disclosed |