Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773609 | 0.87 | LTB4R2 (0.50) | LTB4R2FTOALDH1A1 | |
| SCHEMBL3743779 | 0.85 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL12348453 | 0.83 | LTB4R2 (0.58) | LTB4R2 | |
| SCHEMBL7435938 | 0.83 | LTB4R2 (0.53) | LTB4R2 | |
| SCHEMBL4443620 | 0.81 | ALDH1A1 (0.57) | ALDH1A1 | |
| SCHEMBL2645837 | 0.80 | ALDH1A1 (0.44) | LTB4R2FTOALDH1A1 | |
| SCHEMBL12475941 | 0.80 | LTB4R2 (0.53) | LTB4R2 | |
| SCHEMBL21634961 | 0.79 | ALDH1A1 (0.42) | LTB4R2FTOALDH1A1 | |
| SCHEMBL2645840 | 0.79 | KDM4E (0.47) | LTB4R2FTOALDH1A1 | |
| SCHEMBL31546406 | 0.79 | FTO (0.49) | FTOGPR55ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10300471-B2 | Ruthenium-catalyzed synthesis of biaryl compounds in water | CHICAGO DISCOVERY SOLUTIONS, LLC | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10300471-B2 | Ruthenium-catalyzed synthesis of biaryl compounds in water | RUVBL2, RUVBL1, CYP2W1 | LTB4R2 3351/4885FTO 689/4885GPR55 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.