Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.58 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998734 | 0.94 | AGTR2 (0.57) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL12527631 | 0.92 | AGTR2 (0.57) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL12096488 | 0.92 | AGTR1 (0.69) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL3977106 | 0.92 | AGTR2 (0.62) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL13857701 | 0.91 | AGTR1 (0.53) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL17998745 | 0.91 | AGTR2 (0.57) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL13465074 | 0.90 | AGTR2 (0.59) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL7018921 | 0.89 | AGTR2 (0.58) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL13281995 | 0.89 | AGTR2 (0.53) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 | |
| SCHEMBL17998721 | 0.89 | AGTR2 (0.55) | AGTR2CYP3A4ADORA3ADRA2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746415-A | Synthesis process for continuously preparing azilsartan under microchannel reactor | 南京恒通医药开发有限公司 | 2020-02-04 | — | — | CN | claimed |
| EP-2673274-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL | Jubilant Life Sciences Limited (IN) | 2013-12-18 | — | — | EP | claimed |
| WO-2012107814-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL | JUBILANT LIFE SCIENCES LIMITED (IN) | 2012-08-16 | — | — | WO | claimed |
| CN-108947993-B | Method for green and efficient synthesis of azilsartan in water phase | 常州大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-108752328-B | Simple method for synthesizing azilsartan | 常州大学 | 2020-04-24 | — | — | CN | disclosed |
| EP-2673274-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF AZILSARTAN MEDOXOMIL | JUBILANT GENERICS LTD (IN) | 2019-07-17 | — | — | EP | disclosed |
| EP-2681201-B1 | A METHOD OF MANUFACTURING 2-ETHOXY-1-(2'-((HYDROXYAMINO)IMINOMETHYL)BIPHENYL-4-YL) METHYL)-1H-BENZO(D)IMIDAZOLE-7-CARBOXYLIC ACID AND ITS ESTERS | ZENTIVA KS (CZ) | 2016-08-24 | — | — | EP | disclosed |
| WO-2012157977-A2 | MANUFACTURING METHOD OF HETEROCYCLIC COMPOUND | HANMI FINE CHEMICAL CO., LTD. (KR) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012139536-A1 | A METHOD OF PREPARING 2-ETHOXY-1-((2'-(5-OXO-4,5-DIHYDRO-1,2,4-OXADIAZOL-3-YL)BIPHENYL- 4-YL)METHYL)-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATES AND CONVERSION THEREOF TO AZILSARTAN | ZENTIVA, K.S. (CZ) | 2012-10-18 | — | — | WO | disclosed |
| WO-2012139535-A1 | A METHOD OF PREPARING 2-ETHOXY-1-((2'-(5-OXO-4,5-DIHYDRO-1,2,4-OXADIAZOL-3-YL)BIPHENYL- 4-YL)METHYL)-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATES AND CONVERSION THEREOF TO AZILSARTAN | ZENTIVA, K.S. (CZ) | 2012-10-18 | — | — | WO | disclosed |