SCHEMBL12478397

SCHEMBL12478397

Nc1ccc2c(c1)c(=O)c1c2c2c(=O)c3cc(N)ccc3c2c2c(=O)c3cc(N)ccc3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
NPC1 O15118 4/20 0.48
MAPT P10636 2/20 0.48
GFER P55789 1/20 0.48
PARP1 P09874 3/20 0.44
ALDH1A1 P00352 5/20 0.37
HPGD P15428 4/20 0.37
KMT2A Q03164 3/20 0.37
MAPK1 P28482 2/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
CASP1 P29466 2/20 0.37
CASP7 P55210 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CA1 P00915 1/20 0.37
GLA P06280 1/20 0.37
TYMS P04818 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31206431 1.00 RAB9A (0.48) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL16745388 0.77 RAB9A (0.41) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL16745382 0.77 RAB9A (0.41) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL16745384 0.77 RAB9A (0.41) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL16745385 0.73 RAB9A (0.44) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL16745380 0.73 RAB9A (0.44) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL14174177 0.71 RAB9A (0.50) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL18193055 0.69 NPC1 (0.35) RAB9ASMN1; SMN2NPC1MAPTGFER
SCHEMBL22181654 0.68 ALDH1A1 (0.48) RAB9ASMN1; SMN2NPC1MAPTPARP1
SCHEMBL9222221 0.67 PARP1 (0.59) RAB9ASMN1; SMN2NPC1MAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012110402-A1 TRISAZO COMPOUNDS, PROCESSES FOR PREPARING THEM AND USE THEREOF SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2012-08-23 WO disclosed