Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.44 |
| ▸ | PDCD1LG2 | Q9BQ51 | 17/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962543 | 0.80 | CD274 (0.45) | CD274PDCD1LG2PDCD1TUBB4ATUBB | |
| SCHEMBL6955607 | 0.77 | CD274 (0.48) | CD274PDCD1LG2PDCD1TUBB4ATUBB | |
| SCHEMBL17781570 | 0.76 | PDCD1LG2 (0.43) | CD274PDCD1LG2TUBB4ATUBBTUBA3C | |
| SCHEMBL29599024 | 0.76 | PDCD1LG2 (0.43) | CD274PDCD1LG2TUBB4ATUBBTUBA3C | |
| SCHEMBL12479097 | 0.75 | PDCD1LG2 (0.40) | CD274PDCD1LG2 | |
| SCHEMBL16419630 | 0.74 | PDCD1LG2 (0.44) | CD274PDCD1LG2TUBB4ATUBBTUBA3C | |
| SCHEMBL19237079 | 0.74 | PDCD1LG2 (0.44) | CD274PDCD1LG2TUBB4ATUBBTUBA3C | |
| SCHEMBL29370691 | 0.74 | PDCD1LG2 (0.44) | CD274PDCD1LG2TUBB4ATUBBTUBA3C | |
| SCHEMBL20467095 | 0.74 | ALOX5 (0.41) | CD274PDCD1LG2TUBB4ATUBBTUBA3C | |
| SCHEMBL22790866 | 0.74 | NQO2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012110860-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-08-23 | — | — | WO | disclosed |