⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681900 | 0.84 | — | — | |
| SCHEMBL15851475 | 0.84 | — | — | |
| SCHEMBL29405962 | 0.84 | — | — | |
| SCHEMBL798836 | 0.80 | TSHR (0.35) | — | |
| SCHEMBL15851483 | 0.80 | — | — | |
| SCHEMBL6437670 | 0.80 | — | — | |
| SCHEMBL13826935 | 0.78 | CES2 (0.43) | — | |
| SCHEMBL799407 | 0.76 | CES2 (0.46) | — | |
| SCHEMBL799458 | 0.76 | CES2 (0.46) | — | |
| SCHEMBL13328745 | 0.76 | CES2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569899-B1 | SUBSTITUTED 3-ALKYL- AND 3-ARYLALKYL-1H-INDOL-1-YL-ACETIC ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH CORP (US) | 2006-06-28 | — | — | EP | claimed |
| JP-2006514640-A | — | — | 2006-05-11 | — | — | JP | claimed |
| EP-1569899-A2 | SUBSTITUTED 3-ALKYL AND 3-ARYLALKYL i 1H /i -INDOL-1-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | Wyeth (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2004052853-A2 | SUBSTITUTED 3-ALKYL AND 3-ARYLALKYL 1H-INDOL-1-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | WYETH (US) | 2004-06-24 | — | — | WO | claimed |
| US-20040116488-A1 | Substituted 3-alkyl and 3-arylalkyl 1H-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH | 2004-06-17 | — | — | US | claimed |
| US-5275669-A | Degreasing glass, metal, plastic and fiber surfaces | ALLIEDSIGNAL INC. (US) | 1994-01-04 | — | — | US | claimed |
| WO-2024133913-A2 | SEMIFLUORINATED ALKANE COMPOSITIONS COMPRISING HYOSCYAMINE | NOVALIQ GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-12005033-B2 | Compositions comprising mixtures of semifluorinated alkanes | NOVALIQ GMBH (DE) | 2024-06-11 | — | — | US | disclosed |
| WO-2024108095-A1 | SEMIFLUORINATED ALKANE ANTIBIOTIC COMBINATION COMPOSITIONS FOR TREATMENT OF OCULAR DISORDERS | COFFEY MARTIN (US) | 2024-05-23 | — | — | WO | disclosed |
| US-11987623-B2 | Stabilized antibody compositions | NOVALIQ GMBH (DE) | 2024-05-21 | — | — | US | disclosed |
| EP-4342537-A2 | SEMIFLUORINATED ALKANE COMPOSITIONS | Novaliq GmbH (DE) | 2024-03-27 | — | — | EP | disclosed |
| EP-3100722-B1 | SEMIFLUORINATED ALKANES FOR USE IN SOLUBILIZING MEIBUM | NOVALIQ GMBH (DE) | 2024-03-20 | — | — | EP | disclosed |
| US-11896559-B2 | Opthalmic compositions comprising F6H8 | NOVALIQ GMBH (DE) | 2024-02-13 | — | — | US | disclosed |
| CN-1960958-A | Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers | GREAT LAKES CHEMICAL CORP (US) | 2007-05-09 | — | — | CN | disclosed |
| CN-1957078-A | Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film forming foams, and foams stabilizers | PCBU SERVICES INC (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1938414-A | Production processes and systems, compositions, surfactants, monomer units, metal complexes, phosphate esters, glycols, aqueous film-forming foams, and foam stabilizers | PCBU SERVICES INC (US) | 2007-03-28 | — | — | CN | disclosed |
| US-20060106263-A1 | Processes for production and purification of hydrofluoroolefins | THE CHEMOURS COMPANY FC, LLC | 2006-05-18 | — | — | US | disclosed |
| EP-1193309-B1 | Solvent blend for use in high purity precursor removal | AIR PROD & CHEM (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1193309-A1 | Solvent blend for use in high purity precursor removal | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-04-03 | — | — | EP | disclosed |
| CN-1244859-A | Benzenesulfonamide derivatives and drugs containing the same | HOKURIKU SEIYAKA CO LTD (JP) | 2000-02-16 | — | — | CN | disclosed |