Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | ADH1B | P00325 | 2/20 | 0.46 |
| ▸ | ADH1A | P07327 | 2/20 | 0.46 |
| ▸ | ADH7 | P40394 | 2/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH4 | P08319 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508516 | 1.00 | TSHR (0.69) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| SCHEMBL4211605 | 1.00 | TSHR (0.69) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| SCHEMBL1781797 | 1.00 | TSHR (0.69) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| SCHEMBL7512916 | 1.00 | TSHR (0.69) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| SCHEMBL11508173 | 1.00 | TSHR (0.69) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| SCHEMBL2639821 | 0.97 | TSHR (0.65) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| Bromide SCHEMBL7596439 | 0.97 | TSHR (0.65) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL7512068 | 0.97 | TSHR (0.65) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| Hydrochloric Acid SCHEMBL7512398 | 0.97 | TSHR (0.65) | TSHRALDH1A1PAOXCYP2C19CYP1A2 | |
| Bromide SCHEMBL7601203 | 0.97 | TSHR (0.65) | TSHRALDH1A1PAOXCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017933-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. | 2025-01-16 | — | — | US | disclosed |
| US-20240018242-A1 | METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY | CHILDREN'S MEDICAL CENTER CORPORATION | 2024-01-18 | — | — | US | disclosed |
| US-11685782-B2 | Methods of treating cancer using LSD1 inhibitors in combination with immunotherapy | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-06-27 | — | — | US | disclosed |
| WO-2023091932-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | CARDIFF ONCOLOGY, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-11382872-B2 | LSD1 inhibitors as skeletal muscle hypertrophy inducers | CYTOO (FR) | 2022-07-12 | — | — | US | disclosed |
| WO-2013009372-A1 | PHOSPHORUS-CONTAINING SECONDARY AMINE COMPOUNDS | HUNTSMAN PETROCHEMICAL LLC (US) | 2013-01-17 | — | — | WO | disclosed |
| EP-2467359-A2 | (BIS) UREA AND (BIS) THIOUREA COMPOUNDS AS EPIGENIC MODULATORS OF LYSINE-SPECIFIC DEMETHYLASE 1 AND METHODS OF TREATING DISORDERS | The Johns Hopkins University (US) | 2012-06-27 | — | — | EP | disclosed |
| US-8080626-B2 | Chain extenders | ALBEMARLE CORPORATION (US) | 2011-12-20 | — | — | US | disclosed |
| US-7964695-B2 | Chain extenders | ALBEMARLE CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110137005-A1 | Chain Extenders | ALBEMARLE CORPORATION (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2008039571-A1 | DIAMINE CHAIN EXTENDER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070270566-A1 | Chain Extenders | ALBEMARLE CORPORATION (US) | 2007-11-22 | — | — | US | disclosed |
| US-4957640-A | Corrosion prevention with compositions prepared from organic fatty amines and nitrogen-containing aromatic heterocyclic compounds | THE DOW CHEMICAL COMPANY (US) | 1990-09-18 | — | — | US | disclosed |
| US-4950411-A | OIL AND GAS WELLS | THE DOW CHEMICAL COMPANY (US) | 1990-08-21 | — | — | US | disclosed |
| US-4871848-A | OIL, GAS WELLS CORROSION INHIBITORS | THE DOW CHEMICAL COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4765839-A | PAVING | THE DOW CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| US-4761473-A | CORROSION RESISTANCE OF OIL OR GAS WELLS | THE DOW CHEMICAL COMPANY (US) | 1988-08-02 | — | — | US | disclosed |
| US-4740320-A | REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4724003-A | Asphalt compositions containing anti-stripping additives prepared from hydrocarbyl substituted nitrogen-containing aromatic heterocyclic compounds, aldehydes or ketones and amines | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017933-A1 | CANCER TREATMENT USING LSD1 INHIBITORS AND PLK1 INHIBITORS | PLK1, KDM1B, EZH2 | TSHR 4171/4885ALDH1A1 1850/4885PAOX 2685/4885 |
| US-11685782-B2 | Methods of treating cancer using LSD1 inhibitors in combination with immunotherapy | KDM1B, KDM2A, KDM3B | TSHR 4077/4885ALDH1A1 876/4885PAOX 3102/4885 |
| US-11382872-B2 | LSD1 inhibitors as skeletal muscle hypertrophy inducers | KDM1B, CPT1B, KDM1A | TSHR 2720/4885ALDH1A1 1994/4885PAOX 2157/4885 |
| US-20070270566-A1 | Chain Extenders | DDC, PARG, ODC1 | TSHR 4124/4885ALDH1A1 146/4885PAOX 1145/4885 |
| US-20240018242-A1 | METHODS OF TREATING CANCER USING LSD1 INHIBITORS IN COMBINATION WITH IMMUNOTHERAPY | KDM1B, KDM2A, KDM3B | TSHR 4077/4885ALDH1A1 876/4885PAOX 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.