Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248187 | 1.00 | AGTR2 (0.41) | AGTR2MMP2ALDH1A1POLBMAPT | |
| SCHEMBL1248185 | 1.00 | AGTR2 (0.41) | AGTR2MMP2ALDH1A1POLBMAPT | |
| SCHEMBL1250797 | 0.92 | AGTR2 (0.41) | AGTR2MMP2ALDH1A1POLBMAPT | |
| SCHEMBL1250795 | 0.92 | AGTR2 (0.41) | AGTR2MMP2ALDH1A1POLBMAPT | |
| SCHEMBL1250794 | 0.92 | AGTR2 (0.41) | AGTR2MMP2ALDH1A1POLBMAPT | |
| SCHEMBL995426 | 0.83 | NPC1 (0.45) | MMP2ALDH1A1POLBKMT2AACE | |
| SCHEMBL995430 | 0.83 | NPC1 (0.45) | MMP2ALDH1A1POLBKMT2AACE | |
| SCHEMBL995428 | 0.83 | NPC1 (0.45) | MMP2ALDH1A1POLBKMT2AACE | |
| SCHEMBL16316361 | 0.82 | MMP2 (0.53) | MMP2ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL1250469 | 0.76 | MMP2 (0.62) | AGTR2MMP2ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279737-B1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2012-10-31 | — | — | EP | disclosed |
| EP-2279737-A1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1480644-B1 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | NOVEXEL (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1307457-B1 | AZABICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE AS MEDICINES, IN PARTICULAR AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-04-07 | — | — | EP | disclosed |