Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16816903 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL17498702 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL2336417 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL20049736 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL28966331 | 0.78 | BLM (0.65) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL17768418 | 0.78 | BLM (0.65) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| Methyl Alcohol SCHEMBL28936665 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL3956936 | 0.77 | SMN1; SMN2 (0.78) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL3956933 | 0.77 | SMN1; SMN2 (0.78) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM | |
| SCHEMBL122296 | 0.76 | BLM (0.72) | SMN1; SMN2HIF1ASLC6A2TAAR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2811996-A1 | NEW PEDIATRIC USES OF CABAZITAXEL | Aventis Pharma S.A. (FR) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013117683-A1 | NEW PEDIATRIC USES OF CABAZITAXEL | AVENTIS PHARMA S.A. (FR) | 2013-08-15 | — | — | WO | disclosed |
| WO-2012113897-A1 | ANTITUMORAL COMBINATION COMPRISING CABAZITAXEL AND CISPLATIN | AVENTIS PHARMA S.A. (FR) | 2012-08-30 | — | — | WO | disclosed |