Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16816903 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL17498702 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| Acetone SCHEMBL12483000 | 0.94 | SMN1; SMN2 (0.60) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL20049736 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL17768418 | 0.83 | BLM (0.65) | SMN1; SMN2HIF1ASLC6A2TAAR1CYP1A2 | |
| SCHEMBL28966331 | 0.83 | BLM (0.65) | SMN1; SMN2HIF1ASLC6A2TAAR1CYP1A2 | |
| SCHEMBL3151239 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL8351006 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL1081531 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS | |
| SCHEMBL8219953 | 0.79 | GRM2 (0.53) | SMN1; SMN2HIF1ATAAR1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148723-A1 | MYCOBACTERIUM TUBERCULOSIS COMPOSITIONS AND METHODS | PZA INNOVATION LLC | 2024-05-09 | — | — | US | disclosed |
| CN-114761026-A | Compositions and methods for in vivo synthesis of non-native polypeptides | 斯克利普斯研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-114746099-A | Eukaryotic semisynthetic organisms | 斯克利普斯研究所 | 2022-07-12 | — | — | CN | disclosed |
| CN-112500466-B | Peptidomimetic macrocycles | 艾瑞朗医疗公司 | 2022-05-03 | — | — | CN | disclosed |
| US-20190144406-A1 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME | AVENTIS PHARMA SA (FR) | 2019-05-16 | — | — | US | disclosed |
| US-10160739-B2 | Crystalline forms of dimethoxy docetaxel and methods for preparing the same | AVENTIS PHARMA S.A. (FR) | 2018-12-25 | — | — | US | disclosed |
| US-20180002302-A1 | CRYSTALLINE FORMS OF DIMETHOXY DOCETAXEL AND METHODS FOR PREPARING THE SAME | AVENTIS PHARMA S.A. (FR) | 2018-01-04 | — | — | US | disclosed |
| EP-2964212-A1 | CABAZITAXEL AND ITS USE FOR TREATING METASTATIC PROSTATE CANCERS | Aventis Pharma S.A. (FR) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014135524-A1 | CABAZITAXEL AND ITS USE FOR TREATING METASTATIC PROSTATE CANCERS | AVENTIS PHARMA S.A. (FR) | 2014-09-12 | — | — | WO | disclosed |
| WO-2012113897-A1 | ANTITUMORAL COMBINATION COMPRISING CABAZITAXEL AND CISPLATIN | AVENTIS PHARMA S.A. (FR) | 2012-08-30 | — | — | WO | disclosed |
| EP-2358693-A2 | PREPARATION OF DOCETAXEL | Dr. Reddy's Laboratories, Ltd. (IN) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010059916-A2 | PREPARATION OF DOCETAXEL | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-27 | — | — | WO | disclosed |
| CN-1204329-A | (2R,3S) -3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionic acid taxol-11-en-13 alpha-ester dihydrate and preparation method thereof | RHONE POULENC RORER SA (FR) | 1999-01-06 | — | — | CN | disclosed |