SCHEMBL1248320

SCHEMBL1248320

CC(C)(C)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 10/20 0.55
NAALAD2 Q9Y3Q0 2/20 0.55
RIMKLA Q8IXN7 1/20 0.55
GGH Q92820 1/20 0.52
CYP1A2 P05177 1/20 0.45
TET2 Q6N021 3/20 0.41
KDM4A O75164 2/20 0.41
KDM4C Q9H3R0 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
TET3 O43151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5575587 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHCYP1A2
SCHEMBL9696087 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHCYP1A2
Hydrochloric Acid SCHEMBL5575602 0.98 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHCYP1A2
Hydrochloric Acid SCHEMBL5575609 0.98 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHCYP1A2
SCHEMBL25254699 0.93 FOLH1 (0.48) FOLH1NAALAD2RIMKLAGGH
SCHEMBL9697168 0.89 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGH
SCHEMBL29324448 0.89 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGH
SCHEMBL9696078 0.89 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGH
SCHEMBL7257519 0.87 FOLH1 (0.56) FOLH1NAALAD2RIMKLAGGH
SCHEMBL6237815 0.86 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118638410-A Magnetic nano-particle and preparation method and application thereof 首都医科大学 2024-09-13 CN claimed
CN-118005916-A Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof 四川大学 2024-05-10 CN claimed
CN-116283636-A Method for synthesizing Degu insulin side chain 安徽盈科生物科技有限公司 2023-06-23 CN claimed
US-5952497-A USEFUL IN PEPTIDE, POLYPEPTIDE AND PROTEIN SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 1999-09-14 US claimed
US-20250257045-A1 CAGED GLUTAMATE UNLEASHED BY BLUE AND GREEN LIGHT: INNOVATIVE PHOTOSENSITIVE CONTROL FLORIDA INSTITUTE OF TECH INC (US) 2025-08-14 US disclosed
CN-120022382-A Polyamino acid nanoparticle with lung targeting property, and preparation method and application thereof 苏州大学 2025-05-23 CN disclosed
CN-119677795-A Amphiphilic poly (amino acid) linear block copolymers and nanoparticles thereof for drug delivery applications 纳诺瑟拉生物科学股份有限公司 2025-03-21 CN disclosed
CN-118638410-A Magnetic nano-particle and preparation method and application thereof 首都医科大学 2024-09-13 CN disclosed
CN-118401255-A Paclitaxel conjugated compounds, pharmaceutical compositions comprising the same, and methods of use thereof N1生命股份有限公司 2024-07-26 CN disclosed
CN-118284435-A Drug conjugate based on epsilon-poly-L-lysine, intermediate and application thereof 上海弼领生物技术有限公司 2024-07-02 CN disclosed
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same Sumitomo Pharma Co., Ltd. (JP) 2024-06-25 US disclosed
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same Sumitomo Pharma Co., Ltd. (JP) 2024-06-25 US disclosed
EP-0663840-A1 PREPARATION OF FURTHER DIAGNOSTIC AGENTS Andaris Limited (GB) 1995-07-26 EP disclosed
EP-0458745-B1 Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography BRACCO INT BV (NL) 1994-09-28 EP disclosed
WO-1994008627-A1 PREPARATION OF FURTHER DIAGNOSTIC AGENTS ANDARIS LIMITED (GB) 1994-04-28 WO disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
EP-0533886-A1 PREPARATION OF DIAGNOSTIC AGENTS Delta Biotechnology Limited (GB) 1993-03-31 EP disclosed
EP-0512693-A1 Preparation of diagnostic agents Andaris Limited (GB) 1992-11-11 EP disclosed
WO-1992018164-A1 PREPARATION OF DIAGNOSTIC AGENTS DELTA BIOTECHNOLOGY LIMITED (GB) 1992-10-29 WO disclosed
EP-0458745-A1 Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography BRACCO International B.V. (NL) 1991-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257045-A1 CAGED GLUTAMATE UNLEASHED BY BLUE AND GREEN LIGHT: INNOVATIVE PHOTOSENSITIVE CONTROL GRIA4, GAP43, GGH FOLH1 98/4885NAALAD2 184/4885RIMKLA 244/4885
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same FCGRT, QARS1, INHA FOLH1 4072/4885NAALAD2 984/4885RIMKLA 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.