Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.48 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.48 |
| ▸ | GGH | Q92820 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575587 | 0.93 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL1248320 | 0.93 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL9696087 | 0.93 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGH | |
| Hydrochloric Acid SCHEMBL5575602 | 0.91 | FOLH1 (0.53) | FOLH1NAALAD2RIMKLAGGH | |
| Hydrochloric Acid SCHEMBL5575609 | 0.91 | FOLH1 (0.53) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL7257519 | 0.84 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL9697168 | 0.83 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGHNOD1 | |
| SCHEMBL29324448 | 0.83 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGHNOD1 | |
| SCHEMBL9696078 | 0.83 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGHNOD1 | |
| SCHEMBL22316575 | 0.83 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986381-A | Insulin conjugate and preparation method and application thereof | 北京惠之衡生物科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117986380-A | Insulin conjugate and application thereof | 北京惠之衡生物科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116947978-A | GLP-1 and GIP receptor co-agonist polypeptide derivative, salt and preparation thereof | 北京惠之衡生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116284433-B | Conjugate of insulin and GLP-1 and application thereof | 北京惠之衡生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116410296-A | Long-acting GLP-1 derivative | 吉林惠升生物制药有限公司 | 2023-07-11 | — | — | CN | disclosed |
| WO-2023124847-A1 | LONG-ACTING GLP-1 DERIVATIVE | 北京惠之衡生物科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-116284433-A | Conjugate of insulin and GLP-1 and application thereof | 北京惠之衡生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115850438-B | Long-acting GLP-1 derivative | 北京惠之衡生物科技有限公司 | 2023-05-12 | — | — | CN | disclosed |