SCHEMBL5575587

SCHEMBL5575587

CC(C)(C)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 10/20 0.55
NAALAD2 Q9Y3Q0 2/20 0.55
RIMKLA Q8IXN7 1/20 0.55
GGH Q92820 1/20 0.52
CYP1A2 P05177 1/20 0.45
TET2 Q6N021 3/20 0.41
KDM4A O75164 2/20 0.41
KDM4C Q9H3R0 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
TET3 O43151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696087 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHCYP1A2
SCHEMBL1248320 1.00 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGHCYP1A2
Hydrochloric Acid SCHEMBL5575602 0.98 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHCYP1A2
Hydrochloric Acid SCHEMBL5575609 0.98 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHCYP1A2
SCHEMBL25254699 0.93 FOLH1 (0.48) FOLH1NAALAD2RIMKLAGGH
SCHEMBL9697168 0.89 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGH
SCHEMBL29324448 0.89 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGH
SCHEMBL9696078 0.89 FOLH1 (0.55) FOLH1NAALAD2RIMKLAGGH
SCHEMBL7257519 0.87 FOLH1 (0.56) FOLH1NAALAD2RIMKLAGGH
SCHEMBL6237815 0.86 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005916-A Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof 四川大学 2024-05-10 CN claimed
CN-119677795-A Amphiphilic poly (amino acid) linear block copolymers and nanoparticles thereof for drug delivery applications 纳诺瑟拉生物科学股份有限公司 2025-03-21 CN disclosed
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF FIREFLY BIO, INC. 2024-07-04 US disclosed
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same Sumitomo Pharma Co., Ltd. (JP) 2024-06-25 US disclosed
CN-118005916-A Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof 四川大学 2024-05-10 CN disclosed
CN-118005931-A Polymer nano material with metal binding capacity and preparation and application thereof 四川大学 2024-05-10 CN disclosed
CN-115135694-B Polymeric excipients for drug delivery applications 廷德尔配方服务有限责任公司 2024-03-15 CN disclosed
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. 2024-02-29 US disclosed
US-20230121556-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE TAGWORKS PHARMACEUTICALS B.V. (NL) 2023-04-20 US disclosed
US-11541049-B2 Tetrahydroisoquinoline derivatives, preparation process and use thereof SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-01-03 US disclosed
US-20150291648-A1 N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION BLIRT S.A. (PL) 2015-10-15 US disclosed
EP-2861610-A1 N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION Blirt S.A. (PL) 2015-04-22 EP disclosed
WO-2013186384-A1 N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION BLIRT S.A. (PL) 2013-12-19 WO disclosed
EP-0711177-B1 IMPROVEMENTS RELATING TO THE PREPARATION OF PRODRUGS CANCER RES CAMPAIGN TECH (GB) 2007-05-09 EP disclosed
EP-0744962-B1 METHOD OF STORAGE OF ULTRASONIC GAS SUSPENSIONS BRACCO RESEARCH SA (CH) 2001-09-12 EP disclosed
US-5961956-A GAS MICROBUBBLES IMMOBILISED WITHIN A FROZEN AQUEOUS CARRIER LIQUID; THE IMMOBILISED GAS MICROBUBBLES ARE MICROBUBBLES BOUND BY AN EVANESCENT ENVELOPE OR A TANGIBLE MEMBRANE. BRACCO RESEARCH S.A. (CH) 1999-10-05 US disclosed
US-5830435-A BOUNDING BY ENVELOP OR MEMBRANE BRACCO RESEARCH S.A. (NL) 1998-11-03 US disclosed
US-5827504-A SUSPENSION OF GAS MICROBUBBLES BOUNDED BY EVANESCENT ENVELOPE OR MEMBRANE IMMOBILIZED WITHIN FROZEN CARRIER LIQUID; ECHO IMAGING CONTRAST AGENT BRACCO RESEARCH S.A. (CH) 1998-10-27 US disclosed
EP-0744962-A1 METHOD OF STORAGE OF ULTRASONIC GAS SUSPENSIONS BRACCO RESEARCH S.A. (CH) 1996-12-04 EP disclosed
WO-1996018420-A1 METHOD OF STORAGE OF ULTRASONIC GAS SUSPENSIONS BRACCO RESEARCH S.A. (CH) 1996-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF NR3C1, NR3C2, MC2R FOLH1 2539/4885NAALAD2 1559/4885RIMKLA 4053/4885
US-20230121556-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE LTB4R, LTC4S, LTA4H FOLH1 276/4885NAALAD2 203/4885RIMKLA 2960/4885
US-20150291648-A1 N-SUBSTITUTED SECOND GENERATION DERIVATIVES OF ANTIFUNGAL ANTIBIOTIC AMPHOTERICIN B AND METHODS OF THEIR PREPARATION AND APPLICATION ERG28, LSS, NPC1 FOLH1 3609/4885NAALAD2 205/4885RIMKLA 546/4885
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS TPX2, H1-4, MAPT FOLH1 1549/4885NAALAD2 4083/4885RIMKLA 3147/4885
US-11541049-B2 Tetrahydroisoquinoline derivatives, preparation process and use thereof CYP3A4, CYP3A43, CYP11B2 FOLH1 1828/4885NAALAD2 3108/4885RIMKLA 1649/4885
US-12018093-B2 Hemiasterlin derivatives and antibody-drug conjugates including same FCGRT, QARS1, INHA FOLH1 4072/4885NAALAD2 984/4885RIMKLA 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.