Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709300 | 0.84 | SLC22A1 (0.59) | SLC22A1PRCPADRB2KDM1A | |
| SCHEMBL12486031 | 0.81 | SLC22A1 (0.43) | SLC22A1PRCPDRD2DRD4MEN1 | |
| SCHEMBL12485441 | 0.80 | SLC22A1 (0.43) | SLC22A1PRCPDRD2DRD4MEN1 | |
| SCHEMBL12485686 | 0.80 | GID4 (0.46) | SLC22A1PRCPDRD2DRD4MEN1 | |
| SCHEMBL12486551 | 0.79 | CHRM4 (0.53) | DRD2ADRB2 | |
| SCHEMBL15610746 | 0.79 | PRCP (0.68) | SLC22A1PRCPDRD2DRD4MEN1 | |
| SCHEMBL12486539 | 0.78 | BCHE (0.45) | MEN1KMT2A | |
| SCHEMBL12484520 | 0.78 | BCHE (0.54) | GAA | |
| SCHEMBL12485011 | 0.78 | SLC22A1 (0.40) | SLC22A1PRCPDRD2DRD4MEN1 | |
| SCHEMBL12484586 | 0.77 | CYP2D6 (0.50) | SLC22A1PRCPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012114252-A1 | NOVEL INDOLE AND PYRROLOPYRIDINE AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-08-30 | — | — | WO | disclosed |