SCHEMBL12486197

SCHEMBL12486197

CCC[N+](CC)(CCC)CCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ GLS O94925 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12486311 0.91 CHRM2 (0.56) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL12803087 0.86 CHRM2 (0.48) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL12485338 0.84 CHRM2 (0.49) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL2190238 0.83 CHRM2 (0.46) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL2197282 0.81 CHRM2 (0.47) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL12485341 0.81 CHRM2 (0.47) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL12935859 0.81 CHRM2 (0.66) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL2194119 0.81 CHRM2 (0.57) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL2191608 0.79 CYP2C19 (0.58) CHRM2MEN1CYP1A2CYP2C19KMT2A
SCHEMBL12482194 0.79 CHRM2 (0.63) CHRM2MEN1CYP1A2CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2512409-B1 PHTHALIMIDES AS BLEACH ACTIVATORS HENKEL AG & CO KGAA (DE) 2014-12-17 — — EP disclosed
EP-2512409-B1 PHTHALIMIDES AS BLEACH ACTIVATORS HENKEL AG & CO KGAA (DE) 2014-12-17 — — EP disclosed
US-8328879-B2 Phthalimides as bleach activators HENKEL AG & CO. KGAA (DE) 2012-12-11 — — US disclosed
US-8328879-B2 Phthalimides as bleach activators HENKEL AG & CO. KGAA (DE) 2012-12-11 — — US disclosed
US-20120246841-A1 PHTHALIMIDES AS BLEACH ACTIVATORS HENKEL AG & CO. KGAA (DE) 2012-10-04 — — US disclosed
US-20120246841-A1 PHTHALIMIDES AS BLEACH ACTIVATORS HENKEL AG & CO. KGAA (DE) 2012-10-04 — — US disclosed
WO-2011079974-A2 PHTALIMIDES AS BLEACH ACTIVATORS HENKEL AG & CO. KGAA (DE) 2011-07-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120246841-A1 PHTHALIMIDES AS BLEACH ACTIVATORS KRT18, PPOX, CRYAA CHRM2 4093/4885MEN1 3342/4885CYP1A2 1967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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