Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.52 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872648 | 0.89 | ALDH1A1 (0.50) | TRPM4PTPN22ALDH1A1HSD17B10HIF1A | |
| SCHEMBL19253229 | 0.86 | CYP1A2 (0.46) | TRPM4PTPN22ALDH1A1HSD17B10HIF1A | |
| SCHEMBL2115679 | 0.86 | CYP1A2 (0.50) | TRPM4PTPN22ALDH1A1HSD17B10HIF1A | |
| SCHEMBL4855544 | 0.86 | ALDH1A1 (0.58) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| Benzo[B]Triphenylene SCHEMBL71635 | 0.86 | ALDH1A1 (0.58) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| Benzo[B]Triphenylene SCHEMBL29374595 | 0.86 | ALDH1A1 (0.58) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| Benzo[B]Triphenylene SCHEMBL29628013 | 0.86 | ALDH1A1 (0.58) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| Benzo[B]Triphenylene SCHEMBL17537048 | 0.83 | ALDH1A1 (0.55) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL415471 | 0.83 | ALDH1A1 (0.55) | TRPM4ALDH1A1HSD17B10HIF1ACYP1B1 | |
| SCHEMBL27737884 | 0.83 | CYP1A2 (0.52) | TRPM4PTPN22ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012116013-A2 | SILICA ENCAPSULATED BIOMATERIALS | WACKETT LAWRENCE P (US) | 2012-08-30 | — | — | WO | disclosed |