SCHEMBL4855544

SCHEMBL4855544

c1ccc2cc3c(cc2c1)c1ccccc1c1cc2ccccc2cc13

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
HSD17B10 Q99714 3/20 0.58
HIF1A Q16665 1/20 0.58
CYP1B1 Q16678 1/20 0.58
HPRT1 P00492 3/20 0.56
CYP2A6 P11509 2/20 0.53
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TRPM4 Q8TD43 1/20 0.50
CYP1A2 P05177 1/20 0.50
THRB P10828 1/20 0.50
HPGD P15428 1/20 0.50
NQO1 P15559 1/20 0.48
ALOX12 P18054 1/20 0.47
PAX8 Q06710 1/20 0.43
NQO2 P16083 2/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
HTR2A P28223 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[B]Triphenylene SCHEMBL29628013 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
Benzo[B]Triphenylene SCHEMBL71635 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
Benzo[B]Triphenylene SCHEMBL29374595 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
Benzo[B]Triphenylene SCHEMBL17537048 0.97 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL415471 0.97 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL296990 0.94 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL29981934 0.94 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL14877458 0.94 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL711515 0.94 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1
SCHEMBL55388 0.94 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-5354869-A Fluorescent dyes RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed