Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.47 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451188 | 0.80 | NR5A1 (0.51) | LMNASMN1; SMN2TSHRESR1CYP1A2 | |
| SCHEMBL8928032 | 0.80 | NR5A1 (0.51) | LMNASMN1; SMN2TSHRESR1CYP1A2 | |
| SCHEMBL27861042 | 0.80 | NR5A1 (0.51) | LMNASMN1; SMN2TSHRESR1CYP1A2 | |
| Butane SCHEMBL28029368 | 0.78 | TSHR (0.50) | LMNASMN1; SMN2TSHRESR1CYP1A2 | |
| SCHEMBL10884235 | 0.77 | LMNA (0.49) | LMNASMN1; SMN2TSHRESR1CYP1A2 | |
| SCHEMBL17483400 | 0.75 | ESR1 (0.53) | SMN1; SMN2ESR1ALDH1A1 | |
| SCHEMBL12379279 | 0.75 | ESR1 (0.53) | SMN1; SMN2ESR1ALDH1A1 | |
| SCHEMBL1968988 | 0.75 | ESR1 (0.53) | SMN1; SMN2ESR1ALDH1A1 | |
| SCHEMBL388023 | 0.74 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2TSHRESR1CYP1A2 | |
| SCHEMBL11638205 | 0.74 | CTSK (0.47) | LMNASMN1; SMN2TSHRESR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012115936-A2 | CATALYSTS FOR POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | HONEYWELL INTERNATIONAL INC. (US) | 2012-08-30 | — | — | WO | claimed |
| CN-101356217-A | Blowing agents for forming foam comprising unsaturated fluorocarbons | DU PONT (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-101300296-A | Blowing agents for forming foam comprising unsaturated fluorocarbons | DU PONT (US) | 2008-11-05 | — | — | CN | disclosed |