Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12689728 | 0.80 | MET (0.78) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12486093 | 0.77 | MET (1.00) | MET | |
| SCHEMBL16587293 | 0.76 | MET (0.70) | MET | |
| SCHEMBL12689725 | 0.73 | MET (0.79) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12489807 | 0.72 | MET (0.80) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12482438 | 0.69 | MET (0.60) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL16587280 | 0.69 | MET (0.53) | MET | |
| SCHEMBL18418041 | 0.67 | MET (0.65) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12483199 | 0.67 | MET (0.77) | METPDE3BPDE3A | |
| SCHEMBL16587170 | 0.65 | MET (0.77) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079804-A1 | CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-07-07 | — | — | WO | disclosed |