SCHEMBL16587293

SCHEMBL16587293

c1cnc2scc(Cn3nnc4ncc(-c5cn[nH]c5)nc43)c2c1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12486093 0.82 MET (1.00) MET
SCHEMBL12689725 0.82 MET (0.79) MET
SCHEMBL2572016 0.81 MET (0.68) MET
SCHEMBL12489807 0.81 MET (0.80) MET
SCHEMBL12689728 0.79 MET (0.78) MET
SCHEMBL2575018 0.77 MET (0.72) MET
SCHEMBL12487170 0.76 MET (0.63) MET
SCHEMBL2571941 0.75 MET (1.00) MET
SCHEMBL16587280 0.70 MET (0.53) MET
SCHEMBL12483199 0.69 MET (0.77) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987269-B2 Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor HUTCHISON MEDIPHARMA LIMITED (CN) 2015-03-24 US disclosed