Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30715778 | 0.84 | HTT (0.52) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL28349815 | 0.78 | PTGS2 (0.46) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL2452906 | 0.76 | PTGS2 (0.48) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL8733028 | 0.76 | PTGS2 (0.48) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL1988145 | 0.76 | PTGS2 (0.48) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL2456019 | 0.76 | PTGS2 (0.48) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL17114321 | 0.75 | HTT (0.44) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL10748511 | 0.75 | HTT (0.64) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL324195 | 0.72 | HRH3 (0.48) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL10752271 | 0.72 | ALOX5 (0.44) | HTTHPGDNPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012118233-A1 | ADDITION POLYMERIZATION METHOD, PREPOLYMERIZED CATALYTIC COMPONENT FOR ADDITION POLYMERIZATION, AND METHOD FOR PRODUCING ADDITION POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-07 | — | — | WO | disclosed |