Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138597 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL17859667 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL17859666 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL252121 | 0.82 | TSHR (0.56) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL8060600 | 0.82 | TSHR (0.56) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL29988 | 0.79 | — | — | |
| SCHEMBL27267038 | 0.79 | TSHR (0.48) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| SCHEMBL10906552 | 0.77 | POLB (0.49) | SMN1; SMN2TSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL6147435 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRMAPTKMT2ANPSR1 | |
| Ammonia Solution, Strong SCHEMBL6395522 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897793-B2 | Forming latanoprost; alkylation; reductive desulfurization | INSTYTUT FARMACEUTYCZNY (PL) | 2011-03-01 | — | — | US | disclosed |
| WO-2011016739-A2 | NEW SYNTHONES FOR PREPARATION OF 19-NOR VITAMIN D DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2011-02-10 | — | — | WO | disclosed |