Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 15/20 | 0.63 | |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | FCER2 | P06734 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27955616 | 1.00 | PDF (0.63) | PDFDPP4MMP1FCER2LTA4H | |
| SCHEMBL27955615 | 0.91 | PDF (0.52) | PDFDPP4 | |
| SCHEMBL12487488 | 0.91 | PDF (0.52) | PDFDPP4 | |
| SCHEMBL12486747 | 0.87 | PDF (0.53) | ||
| SCHEMBL12487693 | 0.87 | PDF (0.49) | PDFDPP4MMP1FCER2 | |
| SCHEMBL12487683 | 0.86 | PDF (0.49) | PDFMMP1FCER2 | |
| SCHEMBL12487746 | 0.84 | PDF (0.46) | PDFDPP4 | |
| SCHEMBL12487092 | 0.82 | PDF (0.48) | ||
| SCHEMBL12486976 | 0.81 | PDF (0.44) | PDFMMP1LTA4H | |
| SCHEMBL12487810 | 0.81 | PDF (0.44) | PDFMMP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | claimed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | claimed |
| US-8901119-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2014-12-02 | — | — | US | disclosed |
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |