Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 7/20 | 0.52 | |
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27955615 | 1.00 | PDF (0.52) | PDFDPP4MMP2MMP9MMP12 | |
| SCHEMBL12487552 | 0.91 | PDF (0.63) | PDFDPP4 | |
| SCHEMBL27955616 | 0.91 | PDF (0.63) | PDFDPP4 | |
| SCHEMBL27955613 | 0.88 | PDF (0.43) | PDFMMP2MMP9MMP12F2 | |
| SCHEMBL12487979 | 0.88 | PDF (0.43) | PDFMMP2MMP9MMP12F2 | |
| SCHEMBL12487746 | 0.87 | PDF (0.46) | PDFDPP4F2HPGDCCKBR | |
| SCHEMBL27955608 | 0.87 | F2 (0.42) | PDFDPP4MMP2MMP9MMP12 | |
| SCHEMBL12487608 | 0.87 | F2 (0.42) | PDFDPP4MMP2MMP9MMP12 | |
| SCHEMBL12487693 | 0.86 | PDF (0.49) | PDFDPP4F2EPHX2 | |
| SCHEMBL12487532 | 0.82 | F2 (0.40) | PDFMMP2MMP9MMP12F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827665-A | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2014-05-28 | — | — | CN | disclosed |
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |