Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | HPGDS | O60760 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473057 | 0.85 | MGAM (0.62) | MAOBHPGDSALDH1A1MGAMCYP2A6 | |
| SCHEMBL30494336 | 0.83 | HPGDS (0.66) | MAOBHPGDSALDH1A1MGAMCYP2A6 | |
| SCHEMBL8001650 | 0.81 | MAOB (0.71) | MAOBHPGDSALDH1A1KDM4ENPC1 | |
| SCHEMBL17221411 | 0.81 | MAOB (0.53) | MAOBHPGDSALDH1A1KDM4ENPC1 | |
| SCHEMBL12686639 | 0.80 | PDGFRB (0.45) | MAOBHPGDSMGAM | |
| SCHEMBL29056075 | 0.80 | HPGDS (0.74) | MAOBHPGDS | |
| SCHEMBL336044 | 0.77 | MGAM (0.71) | HPGDSALDH1A1MGAMKDM4ENPC1 | |
| SCHEMBL8001356 | 0.77 | HPGDS (0.70) | MAOBHPGDS | |
| SCHEMBL28028505 | 0.76 | MAOB (0.53) | MAOBHPGDSMGAMKDM4E | |
| Hydrochloric Acid SCHEMBL7902952 | 0.76 | MGAM (0.69) | HPGDSALDH1A1MGAMKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120398-A1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS TRPM8 MODULATORS | PFIZER LIMITED (GB) | 2012-09-13 | — | — | WO | disclosed |