Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.45 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127694 | 0.86 | HDAC1 (0.56) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5118304 | 0.82 | HDAC1 (0.66) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5130249 | 0.79 | HDAC1 (0.51) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5126674 | 0.76 | HDAC1 (0.53) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5131328 | 0.75 | HDAC1 (0.69) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5121971 | 0.75 | HDAC1 (0.69) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5123925 | 0.74 | HDAC1 (0.70) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| Hydrochloric Acid SCHEMBL5131534 | 0.74 | HDAC1 (0.62) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5130255 | 0.73 | RAB9A (0.46) | HDAC1HDAC2HDAC4HDAC3HDAC7 | |
| SCHEMBL5124808 | 0.72 | HDAC1 (0.67) | HDAC1HDAC2HDAC4HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683371-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | Cereno Scientific AB (SE) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012120262-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | LARSSON PIA (SE) | 2012-09-13 | — | — | WO | disclosed |