SCHEMBL12488803

SCHEMBL12488803

O=C(O)c1ccc(-c2c3nc(c(-c4ccc(C(=O)O)cc4)c4[nH]c(c(-c5ccc(C(=O)O)cc5)c5nc(c(-c6ccc(C(=O)O)cc6)c6ccc2[nH]6)C=C5)c2ccccc42)C=C3)cc1

nearest known ligand 0.78

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CYCS P99999 4/20 0.78
▸ TOP1 P11387 4/20 0.77
▸ ENPP2 Q13822 1/20 0.48
▸ ABCG2 Q9UNQ0 1/20 0.45
▸ MAP2K4 P45985 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ TERT O14746 1/20 0.42
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556585 0.89 TOP1 (0.91) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL16418477 0.89 TOP1 (0.91) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL25395869 0.89 TOP1 (0.91) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL25394852 0.89 TOP1 (0.91) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL483511 0.89 TOP1 (0.91) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL12842181 0.89 CYCS (0.97) CYCSTOP1ENPP2ABCG2TERT
SCHEMBL6686149 0.88 TOP1 (0.88) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL6693557 0.88 TOP1 (0.88) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL29520928 0.88 TOP1 (0.88) CYCSTOP1ENPP2ABCG2KDM4E
SCHEMBL19640818 0.88 CYCS (0.91) CYCSTOP1ENPP2ABCG2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114177197-A Use of vanadium compounds for maintaining normoglycemia in a mammal CFM医药控股有限公司 2022-03-15 — — CN disclosed
US-20220040195-A1 USE OF VANADIUM COMPOUNDS FOR MAINTAINING NORMAGLYCEMIA IN A MAMMAL CFM PHARMA HOLDING BV (NL) 2022-02-10 — — US disclosed
CN-107088202-B Use of vanadium compounds for maintaining normoglycemia in a mammal CFM医药控股有限公司 2021-11-30 — — CN disclosed
US-11179401-B2 Use of vanadium compounds for maintaining normaglycemia in a mammal CFM PHARMA HOLDING BV (NL) 2021-11-23 — — US disclosed
US-20200078372-A1 USE OF VANADIUM COMPOUNDS FOR MAINTAINING NORMAGLYCEMIA IN A MAMMAL CFM PHARMA HOLDING BV (NL) 2020-03-12 — — US disclosed
US-10449204-B2 Use of vanadium compounds for maintaining normaglycemia in a mammal CFM PHARMA HOLDING BV (NL) 2019-10-22 — — US disclosed
EP-2683374-B1 USE OF VANADIUM COMPOUNDS FOR MAINTAINING NORMAGLYCEMIA IN A MAMMAL CFM PHARMA HOLDING BV (NL) 2019-09-25 — — EP disclosed
US-20140072647-A1 USE OF VANADIUM COMPOUNDS FOR MAINTAINING NORMAGLYCEMIA IN A MAMMAL CFM PHARMA HOLDING BV 2014-03-13 — — US disclosed
EP-2683374-A1 USE OF VANADIUM COMPOUNDS FOR MAINTAINING NORMAGLYCEMIA IN A MAMMAL CFM Pharma Holding BV (NL) 2014-01-15 — — EP disclosed
WO-2012121596-A1 USE OF VANADIUM COMPOUNDS FOR MAINTAINING NORMAGLYCEMIA IN A MAMMAL CFM PHARMA HOLDING BV (NL) 2012-09-13 — — WO disclosed
Send feedback