SCHEMBL12489191

SCHEMBL12489191

CC(C)C(O)C(C)(C)CO.CC(CO)CO

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.39
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19645 0.90 TRPA1 (0.45) TRPA1TDP1TSHR
SCHEMBL17072023 0.90 TRPA1 (0.45) TRPA1TDP1TSHR
SCHEMBL20721697 0.90 TRPA1 (0.45) TRPA1TDP1TSHR
Isobutanol SCHEMBL6152369 0.88 TSHR (0.45) TRPA1TDP1TSHR
SCHEMBL10818718 0.87 TRPA1 (0.43) TRPA1TDP1TSHR
Glycerin SCHEMBL5175831 0.86 LMNA (0.43) TRPA1TDP1TSHR
SCHEMBL15467886 0.86 TRPA1 (0.34) TRPA1
Ethylene Glycol SCHEMBL2832859 0.85 TRPA1 (0.42) TRPA1TDP1TSHR
Alcohol SCHEMBL6578240 0.85 TRPA1 (0.42) TRPA1TDP1TSHR
Ethylene Glycol SCHEMBL28152293 0.85 TRPA1 (0.42) TRPA1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012049146-A2 POLYURETHANE-BASED SUNSCREEN COMPOSITION CONTAINING SPECIAL FILTER SUBSTANCES BAYER MATERIALSCIENCE AG (DE) 2012-04-19 WO disclosed