Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL12490708

CC(C)CNCC(C)C.N

nearest known ligand 0.47

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.47
ADH1C P00326 1/20 0.47
ADH1A P07327 1/20 0.47
ANPEP P15144 1/20 0.46
CYP2C19 P33261 2/20 0.38
CYP2D6 P10635 1/20 0.38
ESR1 P03372 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
MMP1 P03956 1/20 0.32
MMP8 P22894 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64203 0.96
SCHEMBL29138534 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
Hydrochloric Acid SCHEMBL1062697 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
SCHEMBL27352567 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
SCHEMBL399646 0.92
Fluoride SCHEMBL1055864 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
Methane SCHEMBL9112529 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
Water SCHEMBL11344239 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
Lithium SCHEMBL30576662 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19
SCHEMBL27812939 0.92 ADH1B (0.47) ADH1BADH1CADH1AANPEPCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2686301-A1 MONTELUKAST INTERMEDIATE CAMPHORSULFONIC SALT Laboratorios Lesvi, S.L. (ES) 2014-01-22 EP disclosed
WO-2012123506-A1 MONTELUKAST INTERMEDIATE CAMPHORSULFONIC SALT LABORATORIOS LESVI, S.L. (ES) 2012-09-20 WO disclosed