⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64203 | 0.96 | — | — | |
| SCHEMBL29138534 | 0.92 | ADH1B (0.47) | — | |
| Fluoride SCHEMBL1055864 | 0.92 | ADH1B (0.47) | — | |
| SCHEMBL27352567 | 0.92 | ADH1B (0.47) | — | |
| Hydrochloric Acid SCHEMBL1062697 | 0.92 | ADH1B (0.47) | — | |
| Water SCHEMBL11344239 | 0.92 | ADH1B (0.47) | — | |
| Methane SCHEMBL9112529 | 0.92 | ADH1B (0.47) | — | |
| Ammonia Solution, Strong SCHEMBL12490708 | 0.92 | ADH1B (0.47) | — | |
| Lithium SCHEMBL30576662 | 0.92 | ADH1B (0.47) | — | |
| SCHEMBL28176457 | 0.92 | ADH1B (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022059820-A1 | PRODUCTION METHOD FOR ISOCYANATE COMPOUND COMPRISING NON-CHLORINATED DERIVATIVE, AND COMPOSITION OF SAME | 케이에스랩(주) | 2022-03-24 | — | — | WO | claimed |
| US-20100137577-A1 | ADENOSINE DERIVATIVES, METHOD FOR THE SYNTHESIS THEREOF, AND THE PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | FUTURE MEDICINE CO., LTD. (KR) | 2010-06-03 | — | — | US | claimed |
| EP-2142549-A1 | ADENOSINE DERIVATIVES, METHOD FOR THE SYNTHESIS THEREOF, AND THE PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | FM Therapeutics Co., Ltd. (KR) | 2010-01-13 | — | — | EP | claimed |
| WO-2008108508-A1 | ADENOSINE DERIVATIVES, METHOD FOR THE SYNTHESIS THEREOF, AND THE PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE INFLAMMATORY DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | FM THERAPEUTICS CO., LTD. (KR) | 2008-09-12 | — | — | WO | claimed |
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | claimed |
| EP-0059094-B1 | NOVEL CYCLOHEPTANES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-07-31 | — | — | EP | claimed |
| US-12534458-B2 | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors | MERCK SHARP & DOHME LLC (US) | 2026-01-27 | — | — | US | disclosed |
| US-12331022-B2 | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors | MERCK SHARP & DOHME LLC (US) | 2025-06-17 | — | — | US | disclosed |
| CN-112119076-B | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors | 默沙东有限责任公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-3788043-B1 | SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |
| US-12083140-B2 | Pharmaceutical composition for preventing and treating glaucoma, containing adenosine derivative | FUTURE MEDICINE CO., LTD. (KR) | 2024-09-10 | — | — | US | disclosed |
| EP-4423069-A1 | INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| US-12071411-B2 | Inhibitors of HIF-2α and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| CN-1085941-A | The liquid washing agent that contains peptide trifluoromethyl ketone | PROCTER & GAMBLE (US) | 1994-04-27 | — | — | CN | disclosed |
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0146837-B1 | CYCLOHEXENONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS HERBICIDAL COMPOUNDS | BASF Aktiengesellschaft (DE) | 1988-03-23 | — | — | EP | disclosed |
| US-4659367-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0146837-A2 | Cyclohexenone derivatives, process for their preparation and their application as herbicidal compounds | BASF Aktiengesellschaft (DE) | 1985-07-03 | — | — | EP | disclosed |
| US-4140854-A | ANTISECRETORY, ANTIULCER | STERLING DRUG INC. (US) | 1979-02-20 | — | — | US | disclosed |