Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21938918 | 0.81 | CYP19A1 (0.37) | CYP19A1KDM4EPOLBL3MBTL1HTT | |
| SCHEMBL12491809 | 0.81 | ERN1 (0.54) | CYP19A1KDM4EPOLBL3MBTL1HTT | |
| SCHEMBL21938917 | 0.79 | CDK4 (0.38) | CYP19A1KDM4EPOLBL3MBTL1HTT | |
| SCHEMBL7669530 | 0.76 | MAPT (0.64) | CYP19A1KDM4EPOLBL3MBTL1ERN1 | |
| SCHEMBL4918747 | 0.74 | ALDH1A1 (0.52) | KDM4EPOLBL3MBTL1CTDSP1ERN1 | |
| SCHEMBL29941258 | 0.74 | ALDH1A1 (0.52) | KDM4EPOLBL3MBTL1CTDSP1ERN1 | |
| SCHEMBL29266725 | 0.73 | CYP3A4 (0.35) | CYP19A1KDM4EPOLBL3MBTL1HTT | |
| SCHEMBL25385602 | 0.73 | TTR (0.67) | KDM4EPOLBL3MBTL1ERN1ALDH1A1 | |
| SCHEMBL22400345 | 0.73 | TTR (0.50) | CYP19A1KDM4EPOLBL3MBTL1HTT | |
| SCHEMBL5648278 | 0.73 | ERN1 (0.50) | CYP19A1KDM4EPOLBL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130121919-A1 | HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130121919-A1 | HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF | EP300, KAT2A, NAA40 | CYP19A1 4556/4885KDM4E 1505/4885POLB 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.