Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.80 |
| ▸ | HTR1A | P08908 | 7/20 | 0.72 |
| ▸ | DRD4 | P21917 | 7/20 | 0.72 |
| ▸ | HTR2A | P28223 | 7/20 | 0.72 |
| ▸ | HTR2C | P28335 | 7/20 | 0.72 |
| ▸ | HTR7 | P34969 | 7/20 | 0.72 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.72 |
| ▸ | HRH2 | P25021 | 6/20 | 0.72 |
| ▸ | DRD3 | P35462 | 6/20 | 0.72 |
| ▸ | HTR2B | P41595 | 6/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.72 |
| ▸ | HRH1 | P35367 | 5/20 | 0.72 |
| ▸ | DRD1 | P21728 | 5/20 | 0.71 |
| ▸ | DRD5 | P21918 | 5/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.71 |
| ▸ | HTR6 | P50406 | 5/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.71 |
| ▸ | HTR5A | P47898 | 4/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Seperidol SCHEMBL124936 | 0.99 | DRD2 (0.78) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL11382049 | 0.88 | DRD2 (0.62) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL11858251 | 0.88 | DRD2 (0.74) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL11463963 | 0.87 | DRD2 (0.62) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL11609688 | 0.86 | DRD2 (0.61) | DRD2HTR1ADRD4HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11469274 | 0.86 | DRD2 (0.61) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL14282239 | 0.84 | OPRM1 (0.76) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL9054984 | 0.84 | DRD2 (1.00) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL11846146 | 0.84 | DRD2 (0.61) | DRD2HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL11715692 | 0.83 | OPRM1 (0.65) | DRD2HTR1ADRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931320-B1 | MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME | FLAMEL IRELAND LTD (IE) | 2022-06-15 | — | — | EP | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-8268352-B2 | Modified release composition for highly soluble drugs | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-18 | — | — | US | claimed |
| US-8263125-B2 | Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| US-20100234288-A1 | SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION ON THE BASIS OF RELEASE SYSTEM COMPRISING AN ACID-SOLUBLE POLYMER AND A pH-DEPENDENT POLYMER | PANACEA BIOTEC LTD (IN) | 2010-09-16 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-20090220611-A1 | Microparticles With Modified Release of At Least One Active Principle and Oral Pharmaceutical Form Comprising Same | FLAMEL TECHNOLOGIES, S.A. (FR) | 2009-09-03 | — | — | US | claimed |
| EP-2004150-A1 | SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION ON THE BASIS OF A RELEASE SYSTEM COMPRISING AN ACID-SOLUBLE POLYMER AND A PH-DEPENDENT POLYMER. | Panacea Biotec Ltd. (IN) | 2008-12-24 | — | — | EP | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007036671-A2 | MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL GALENIC FORM COMPRISING SAME | FLAMEL TECHNOLOGIES (FR) | 2007-04-05 | — | — | WO | claimed |
| US-20060024365-A1 | Novel dosage form | VAYA NAVIN | 2006-02-02 | — | — | US | claimed |
| US-20060018933-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| US-20060018934-A1 | Novel drug delivery system | TORRENT PHARMACEUTICALS LIMITED (IN) | 2006-01-26 | — | — | US | claimed |
| EP-1044023-B1 | A COVALENT CONJUGATE OF CLOZAPINE WITH A FATTY ACID AND ITS USE FOR TREATING SCHIZOPHRENIA | LUITPOLD PHARM INC (US) | 2005-05-25 | — | — | EP | claimed |
| US-6197764-B1 | COMPLEX WITH FATTY ACID; THERAPY FOR PSYCHOLOGICAL DISORDERS | PROTARGA, INC. | 2001-03-06 | — | — | US | claimed |
| EP-1044023-A1 | A COVALENT CONJUGATE OF CLOZAPINE WITH A FATTY ACID AND ITS USE FOR TREATING SCHIZOPHRENIA | Protarga Inc. (US) | 2000-10-18 | — | — | EP | claimed |
| US-5955459-A | Fatty acid-antipsychotic compositions and uses thereof | NEUROMEDICA, INC. (US) | 1999-09-21 | — | — | US | claimed |
| WO-1999026661-A1 | A COVALENT CONJUGATE OF CLOZAPINE WITH A FATTY ACID AND ITS USE FOR TREATING SCHIZOPHRENIA | PROTARGA INC. (US) | 1999-06-03 | — | — | WO | claimed |
| US-4565821-A | 4-PIPERADINO-4*-FLUOROBUTYROPHENONES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 1986-01-21 | — | — | US | claimed |