Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.63 |
| ▸ | SHBG | P04278 | 5/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | STS | P08842 | 4/20 | 0.61 |
| ▸ | PGR | P06401 | 4/20 | 0.61 |
| ▸ | AR | P10275 | 4/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.61 |
| ▸ | SNCA | P37840 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489438 | 1.00 | ESR1 (0.63) | ESR1SHBGESR2HSD17B10LMNA | |
| SCHEMBL7867608 | 1.00 | ESR1 (0.63) | ESR1SHBGESR2HSD17B10LMNA | |
| Methoxymethane SCHEMBL4279943 | 0.96 | ESR1 (0.60) | ESR1SHBGESR2HSD17B10LMNA | |
| SCHEMBL8712230 | 0.85 | ESR1 (0.52) | ESR1SHBGESR2HSD17B10LMNA | |
| SCHEMBL10533710 | 0.85 | SRD5A2 (0.57) | ESR1SHBGESR2HSD17B10LMNA | |
| SCHEMBL5682148 | 0.84 | LMNA (0.64) | ESR1ESR2HSD17B10LMNASTS | |
| SCHEMBL1246984 | 0.84 | LMNA (0.64) | ESR1ESR2HSD17B10LMNASTS | |
| SCHEMBL5679838 | 0.84 | LMNA (0.64) | ESR1ESR2HSD17B10LMNASTS | |
| SCHEMBL5154685 | 0.84 | LMNA (0.64) | ESR1ESR2HSD17B10LMNASTS | |
| SCHEMBL5679791 | 0.84 | LMNA (0.64) | ESR1ESR2HSD17B10LMNASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278880-A1 | STEROID TREATMENT FOR HOT FLASHES | Pherin Pharmaceuticals, Inc. (US) | 2011-02-02 | — | — | EP | claimed |
| US-20100120729-A1 | PHEROMONE-CONTAINING COSMETIC AGENTS | HENKEL AG & CO. KGAA (DE) | 2010-05-13 | — | — | US | claimed |
| EP-2148650-A2 | PHEROMONE-CONTAINING COSMETIC SUBSTANCES | Henkel AG & Co. KGaA (DE) | 2010-02-03 | — | — | EP | claimed |
| US-20090258040-A1 | STEROID TREATMENT FOR HOT FLASHES | PHERIN PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | claimed |
| WO-2009126825-A1 | STEROID TREATMENT FOR HOT FLASHES | PHERIN PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | WO | claimed |
| WO-2008138651-A2 | PHEROMONE-CONTAINING COSMETIC SUBSTANCES | HENKEL AG & CO. KGAA (DE) | 2008-11-20 | — | — | WO | claimed |
| US-20070265238-A1 | METHOD FOR ACCELERATING REENTRAINMENT OF A CIRCADIAN RHYTHM | JECHURA TAMMY | 2007-11-15 | — | — | US | claimed |
| EP-0891188-A4 | STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN BLOOD LEVELS OF LH OR FSH | PHERIN PHARM INC (US) | 2004-09-01 | — | — | EP | claimed |
| US-6331534-B1 | ADMINISTERING EFFECTIVE AMOUNT OF STEROID WITHIN NASAL PASSAGE OF INDIVIDUAL SUCH THAT IT BINDS SPECIFICALLY TO RECEPTORS ON SURFACE OF NASAL NEUROEPITHELIAL CELLS IN VOMERONASAL ORGAN | PHERIN PHARMACEUTICALS, INC. | 2001-12-18 | — | — | US | claimed |
| WO-2001041732-A1 | COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF ACTIVE AGENTS TO THE BRAIN | GORE STANLEY L (CA) | 2001-06-14 | — | — | WO | claimed |
| JP-2000504025-A | — | — | 2000-04-04 | — | — | JP | claimed |
| EP-0891188-A1 | STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN BLOOD LEVELS OF LH OR FSH | Pherin Pharmaceuticals, Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| EP-0562843-B1 | Fragrance compositions and other compositions which contain human pheromones | EROX CORP (US) | 1998-12-23 | — | — | EP | claimed |
| US-5783571-A | SUBSTITUTED TETRAENE STEROIDS FOR CONTROLLING GLANDULAR FUNCTION | PHERIN CORPORATION (US) | 1998-07-21 | — | — | US | claimed |
| EP-0715517-A1 | ESTRENE STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN HYPOTHALAMIC FUNCTION AND RELATED PHARMACEUTICAL COMPOSITIONS AND METHODS | PHERIN CORPORATION (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1994028903-A1 | ESTRENE STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN HYPOTHALAMIC FUNCTION AND RELATED PHARMACEUTICAL COMPOSITIONS AND METHODS | PHERIN CORPORATION (US) | 1994-12-22 | — | — | WO | claimed |
| US-5278141-A | Fragrance compositions containing human pheromones | EROX CORPORATION (US) | 1994-01-11 | — | — | US | claimed |
| US-5272134-A | Fragrance compositions and other compositions which contain human pheromones | EROX CORPORATION (US) | 1993-12-21 | — | — | US | claimed |
| WO-1993018742-A1 | FRAGRANCE COMPOSITIONS AND OTHER COMPOSITIONS WHICH CONTAIN HUMAN PHEROMONES | EROX CORPORATION (US) | 1993-09-30 | — | — | WO | claimed |
| EP-0562843-A2 | Fragrance compositions and other compositions which contain human pheromones | EROX CORPORATION (US) | 1993-09-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120729-A1 | PHEROMONE-CONTAINING COSMETIC AGENTS | SHBG, KRT18, CYP17A1 | ESR1 24/4885SHBG 1/4885ESR2 34/4885 |
| US-20090258040-A1 | STEROID TREATMENT FOR HOT FLASHES | CYP19A1, SHBG, HSD17B11 | ESR1 7/4885SHBG 2/4885ESR2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.