Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | CA6 | P23280 | 3/20 | 0.58 |
| ▸ | CA5A | P35218 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495039 | 0.93 | HPGD (0.66) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL11688371 | 0.88 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL3094869 | 0.83 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL1728080 | 0.83 | HPGD (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL1728078 | 0.83 | HPGD (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL18143897 | 0.81 | HPGD (0.60) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL12494123 | 0.80 | HPGD (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL11631231 | 0.78 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL11629279 | 0.77 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL11628681 | 0.77 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107411-B2 | Indolecarboxamides and benzimidazolecarboxamides as insecticides and acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-18 | — | — | US | disclosed |
| EP-2683688-B1 | INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20140088167-A1 | INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| EP-2683688-A1 | INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES | Bayer Intellectual Property GmbH (DE) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012119984-A1 | INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES | BAYER CROPSCIENCE AG (DE) | 2012-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088167-A1 | INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES | AADAC, DDT, AANAT | NPC1 3469/4885RAB9A 2213/4885SMN1; SMN2 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.